Chemo-enzymatic synthesis and biological evaluation of photolabile nicotinic acid adenine dinuclotide phosphate (NAADP+).

A chemo-enzymatic synthesis of novel caged NAADP+ without the formation of multiple cage compounds has been achieved. The biological activity of the caged NAADP+ was demonstrated by its fast uncaging in intact sea-urchin eggs.

Bibliographic Details
Main Authors: Parkesh, R, Vasudevan, SR, Berry, A, Galione, A, Dowden, J, Churchill, G
Format: Journal article
Language:English
Published: 2007