Pre-labelling versus direct labelling of anthrax proteins for imaging of matrix metalloproteinases activity using DOTA-GA

Pre-labelling versus direct labelling of anthrax proteins for imaging of matrix metalloproteinases activity using DOTA-GA

INTRODUCTION:Increased activity of matrix metalloproteases (MMPs) is associated with reduced survival in several cancer subtypes. Aiming to produce an MMP tumour cell-selective cytotoxin, we genetically modified both components of the AB-type lethal toxin from Bacillus anthracis. Component A, Protec...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Xavier, M-AE, Liu, S, Leppla, SH, Cornelissen, B
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	Elsevier 2019

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