Novel nucleotide triphosphates as potent P2Y2 agonists.

Novel nucleotide triphosphates as potent P2Y2 agonists.

The synthesis and P2Y2 activities of a novel series of nucleoside triphosphates are described. Many of these compounds were potent agonists of the P2Y2 receptor.

書目詳細資料
Main Authors:	Brookings, D, Davenport, R, Davis, J, Galvin, F, Lloyd, S, Mack, SR, Owens, R, Sabin, V, Wynn, J
格式:	Journal article
語言:	English
出版:	2007

相似書籍

Novel nucleotide triphosphates as potent P2Y2 agonists with enhanced stability over UTP.
由: Davenport, R, et al.
出版: (2007)

Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs.
由: Scott J Hughes, et al.
出版: (2016-01-01)

Correction: Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs.
由: Scott J Hughes, et al.
出版: (2016-01-01)

Measurement of Nucleotide Triphosphate Sugar Transferase Activity via Generation of Pyrophosphate
由: Kaisei Maeda, et al.
出版: (2015-04-01)

Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6
由: Antje Brüser, et al.
出版: (2017-05-01)

PCR amplification of GC-rich DNA regions using the nucleotide analog N4-methyl-2′-deoxycytidine 5′-triphosphate
由: Cyntia R. Flores-Juárez, et al.
出版: (2016-10-01)

Allosteric Activation of SARS-CoV-2 RNA-Dependent RNA Polymerase by Remdesivir Triphosphate and Other Phosphorylated Nucleotides
由: Bing Wang, et al.
出版: (2021-06-01)

Functionalized Oxoindolin Hydrazine Carbothioamide Derivatives as Highly Potent Inhibitors of Nucleoside Triphosphate Diphosphohydrolases
由: Saira Afzal, et al.
出版: (2020-11-01)

Non-nucleotide Agonists Triggering P2X7 Receptor Activation and Pore Formation
由: Francesco Di Virgilio, et al.
出版: (2018-02-01)

Inosine triphosphate pyrophosphatase from Trypanosoma brucei cleanses cytosolic pools from deaminated nucleotides
由: Antonio E. Vidal, et al.
出版: (2022-04-01)

A Non-Nucleotide STING Agonist MSA-2 Synergized with Manganese in Enhancing STING Activation to Elicit Potent Anti-RNA Virus Activity in the Cells
由: Hanrui Lin, et al.
出版: (2023-10-01)

Correction to 'Running out of time: the decline of channel activity and nucleotide activation in adenosine triphosphate-sensitive K-channels'.
由: Proks, P, et al.
出版: (2016)

Dipotassium trisodium triphosphate, K2Na3P3O10
由: Meryem Moutataouia, et al.
出版: (2012-05-01)

Identification of MSA-2: An oral antitumor non-nucleotide STING agonist
由: Jianhua Liu, et al.
出版: (2021-01-01)

Adenosine A2A receptor agonists with potent antiplatelet activity
由: Eduardo Fuentes, et al.
出版: (2018-04-01)

Adenosine Triphosphate Release and P2 Receptor Signaling in Piezo1 Channel-Dependent Mechanoregulation
由: Linyu Wei, et al.
出版: (2019-11-01)

Unanticipated Characteristics of a Selective, Potent Neuromedin‑U Receptor 2 Agonist
由: Suneet Mehrotra, et al.
出版: (2022-05-01)

Adenosine thiamine triphosphate and adenosine thiamine triphosphate hydrolase activity in animal tissues
由: A. F. Makarchikov, et al.
出版: (2018-07-01)

Optimized Method for the Synthesis of Alkyne-Modified 2′-Deoxynucleoside Triphosphates
由: Viktoriya E. Kuznetsova, et al.
出版: (2024-10-01)

Antidipsogenic effects of central adenosine-5'-triphosphate
由: D.R.G. de Faria, et al.
出版: (2009-01-01)

Potent achiral agonists of the growth hormone secretagogue (ghrelin) receptor. Part 2: Lead optimisation.
由: Witherington, J, et al.
出版: (2008)

Potent, selective adenosine Al agonists as potential analgesics
由: Beswick, P, et al.
出版: (2004)

Total Synthesis of (±)-Quinagolide: A Potent D2 Receptor Agonist for the Treatment of Hyperprolactinemia
由: Subhash P. Chavan, et al.
出版: (2019-05-01)

Novel 2-mercapto imidazole and triazole derivatives as potent TGR5 receptor agonists
由: Sameer Agarwal, et al.
出版: (2019-03-01)

The CoxD protein, a novel AAA+ ATPase involved in metal cluster assembly: hydrolysis of nucleotide-triphosphates and oligomerization.
由: Tobias Maisel, et al.
出版: (2012-01-01)

Delta12-prostaglandin D2 is a potent and selective CRTH2 receptor agonist and causes activation of human eosinophils and Th2 lymphocytes.
由: Gazi, L, et al.
出版: (2005)

Data set on the synthesis and properties of 2′,3′-dideoxyuridine triphosphate conjugated to SiO2 nanoparticles
由: Svetlana V. Vasilyeva, et al.
出版: (2018-12-01)

Highly Potent, Stable, and Selective Dimeric Hetarylpropylguanidine-Type Histamine H2 Receptor Agonists
由: Steffen Pockes, et al.
出版: (2018-03-01)

The beta2-adrenergic agonist salbutamol is a potent suppressor of established collagen-induced arthritis: mechanisms of action.
由: Malfait, A, et al.
出版: (1999)

Expression of Ectonucleoside Triphosphate Diphosphohydrolase 2 (NTPDase2) Is Negatively Regulated Under Neuroinflammatory Conditions and
由: Milorad Dragic, et al.
出版: (2022-05-01)

Effects of 4(1H)-quinolinone derivative, a novel non-nucleotide allosteric purinergic P2Y 2 agonist, on cardiomyocytes in neonatal rats
由: Kensuke Sakuma, et al.
出版: (2017-07-01)

Cytidine triphosphate:phosphatidic acid cytidyltransferase in Escherichia coli
由: James R. Carter, Jr.
出版: (1968-11-01)

New Algorithm of Stress Echocardiography with Adenosine Triphosphate
由: N. Yu. Nelassov, et al.
出版: (2020-11-01)

Creation of Potent Vitamin D Receptor Agonists and Antagonists with 2?-(?-Hydroxyalkylation) Concept to the seco-Steroid Skeleton
由: Atsushi Kittaka
出版: (2018-12-01)

Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity
由: Ning Wang, et al.
出版: (2019-08-01)

Model Linking Plasma and Intracellular Tenofovir/Emtricitabine with Deoxynucleoside Triphosphates.
由: Xinhui Chen, et al.
出版: (2016-01-01)

Nanoparticulate STING agonists are potent lymph node–targeted vaccine adjuvants
由: Crespo, Monica P., et al.
出版: (2015)

Lithocholic Acid Amides as Potent Vitamin D Receptor Agonists
由: Ayana Yoshihara, et al.
出版: (2022-01-01)

Discovery of Kynurenines Containing Oligopeptides as Potent Opioid Receptor Agonists
由: Edina Szűcs, et al.
出版: (2020-02-01)

Structure-based discovery of potent and selective melatonin receptor agonists
由: Nilkanth Patel, et al.
出版: (2020-03-01)