Structural and mechanistic insights into ras association domains of phospholipase C epsilon.

Ras proteins signal to a number of distinct pathways by interacting with diverse effectors. Studies of ras/effector interactions have focused on three classes, Raf kinases, ral guanylnucleotide-exchange factors, and phosphatidylinositol-3-kinases. Here we describe ras interactions with another effec...

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Bibliographic Details
Main Authors: Bunney, T, Harris, R, Gandarillas, N, Josephs, M, Roe, S, Sorli, S, Paterson, H, Rodrigues-Lima, F, Esposito, D, Ponting, C, Gierschik, P, Pearl, L, Driscoll, P, Katan, M
Format: Journal article
Language:English
Published: 2006