Induction of tumour rejection by B7.1 and IL-2 expressing tumour cells
Prif Awduron: | Gaken, J, Hirst, W, Darling, D, GaleaLauri, J, Buggins, A, Kuiper, M, Souberbielle, B, Towner, P, Hollingsworth, S, Mufti, G, Farzaneh, F |
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Fformat: | Journal article |
Cyhoeddwyd: |
1997
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Eitemau Tebyg
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Induction of tumour rejection by autologous and allogeneic tumour cells expressing B7.1 and IL-2.
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In vitro immune modulation by antibodies coupled to tumour cells.
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Irradiated NC adenocarcinoma cells transduced with both B7.1 and interleukin-2 induce CD4+-mediated rejection of established tumors.
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A polycistronic retroviral vector encoding hB7-1 (CD80) and hIL-2 for ex vivo cancer gene therapy.
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