Synthetic Inositol phosphate analogs reveal that PPIP5K2 has a surface-mounted substrate capture site that is a target for drug discovery

Synthetic Inositol phosphate analogs reveal that PPIP5K2 has a surface-mounted substrate capture site that is a target for drug discovery

Diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) is one of the mammalian PPIP5K isoforms responsible for synthesis of diphosphoinositol polyphosphates (inositol pyrophosphates; PP-InsPs), regulatory molecules that function at the interface of cell signaling and organismic homeostasis. The deve...

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Dettagli Bibliografici
Autori principali:	Wang, H, Godage, H, Riley, A, Weaver, J, Shears, S, Potter, B
Natura:	Journal article
Lingua:	English
Pubblicazione:	Elsevier 2014

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