CD94/NKG2 is the predominant inhibitory receptor involved in recognition of HLA-G by decidual and peripheral blood NK cells.
Prior studies demonstrated that NK cells isolated from adult peripheral blood kill the HLA-A-, HLA-B-, and HLA-C-deficient B lymphoblastoid cell line 721.221, but many are unable to kill 721.221 cells transfected with HLA-G, a molecule expressed preferentially on fetal cytotrophoblasts. To determine...
Huvudupphovsmän: | Söderström, K, Corliss, B, Lanier, L, Phillips, J |
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Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
1997
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