Germline determinants of 5-fluorouracil drug toxicity and patient survival in colorectal cancer

<p>Despite a decade of publications investigating the effect of germline polymorphisms on both toxicity related to treatment with 5-fluorouracil-based (5-FU) chemotherapy and prognosis following diagnosis with colorectal cancer (CRC), few genetic biomarkers have been identified convincingly. F...

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Bibliographic Details
Main Author: Rosmarin, DN
Other Authors: Tomlinson, I
Format: Thesis
Language:English
Published: 2013
Subjects: