Enhancing contrast agents and radiotracers performance through hyaluronic acid-coating in neuroradiology and nuclear medicine
The use of hyaluronic acid nanoshells has been proposed to encapsulate prodrugs and exploit the mechanisms of interactions between living cells, like endocytes or cancer cells and hyaluronic acid, which is a natural component of the extracellular matrix. In this review we describe the potential and...
| Main Authors: | , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Hellenic Society of Nuclear Medicine
2017
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| _version_ | 1826298902155886592 |
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| author | Ganau, M Syrmos, N D'Arco, F Ganau, L Chibbaro, S Prisco, L Ligarotti, G Ambu, R Soddu, A |
| author_facet | Ganau, M Syrmos, N D'Arco, F Ganau, L Chibbaro, S Prisco, L Ligarotti, G Ambu, R Soddu, A |
| author_sort | Ganau, M |
| collection | OXFORD |
| description | The use of hyaluronic acid nanoshells has been proposed to encapsulate prodrugs and exploit the mechanisms of interactions between living cells, like endocytes or cancer cells and hyaluronic acid, which is a natural component of the extracellular matrix. In this review we describe the potential and the limits of this promising research trend and discuss the theoretical advantages of such an engineering approach. Is it a possible scalability to increase the efficacy and biodegradability of molecules like contrast media and radiotracers especially for neuroradiology and nuclear medicine studies. |
| first_indexed | 2024-03-07T04:53:48Z |
| format | Journal article |
| id | oxford-uuid:d5e36fd1-84e7-4f19-9812-ae17f1e9d263 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:53:48Z |
| publishDate | 2017 |
| publisher | Hellenic Society of Nuclear Medicine |
| record_format | dspace |
| spelling | oxford-uuid:d5e36fd1-84e7-4f19-9812-ae17f1e9d2632022-03-27T08:29:17ZEnhancing contrast agents and radiotracers performance through hyaluronic acid-coating in neuroradiology and nuclear medicineJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d5e36fd1-84e7-4f19-9812-ae17f1e9d263EnglishSymplectic Elements at OxfordHellenic Society of Nuclear Medicine2017Ganau, MSyrmos, ND'Arco, FGanau, LChibbaro, SPrisco, LLigarotti, GAmbu, RSoddu, AThe use of hyaluronic acid nanoshells has been proposed to encapsulate prodrugs and exploit the mechanisms of interactions between living cells, like endocytes or cancer cells and hyaluronic acid, which is a natural component of the extracellular matrix. In this review we describe the potential and the limits of this promising research trend and discuss the theoretical advantages of such an engineering approach. Is it a possible scalability to increase the efficacy and biodegradability of molecules like contrast media and radiotracers especially for neuroradiology and nuclear medicine studies. |
| spellingShingle | Ganau, M Syrmos, N D'Arco, F Ganau, L Chibbaro, S Prisco, L Ligarotti, G Ambu, R Soddu, A Enhancing contrast agents and radiotracers performance through hyaluronic acid-coating in neuroradiology and nuclear medicine |
| title | Enhancing contrast agents and radiotracers performance through hyaluronic acid-coating in neuroradiology and nuclear medicine |
| title_full | Enhancing contrast agents and radiotracers performance through hyaluronic acid-coating in neuroradiology and nuclear medicine |
| title_fullStr | Enhancing contrast agents and radiotracers performance through hyaluronic acid-coating in neuroradiology and nuclear medicine |
| title_full_unstemmed | Enhancing contrast agents and radiotracers performance through hyaluronic acid-coating in neuroradiology and nuclear medicine |
| title_short | Enhancing contrast agents and radiotracers performance through hyaluronic acid-coating in neuroradiology and nuclear medicine |
| title_sort | enhancing contrast agents and radiotracers performance through hyaluronic acid coating in neuroradiology and nuclear medicine |
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