Hydration and interactions in protein solutions containing concentrated electrolytes studied by small-angle scattering.

During protein crystallization and purification, proteins are commonly found in concentrated salt solutions. The exact interplay of the hydration shell, the salt ions, and protein-protein interactions under these conditions is far from being understood on a fundamental level, despite the obvious pra...

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Main Authors: Zhang, F, Roosen-Runge, F, Skoda, M, Jacobs, R, Wolf, M, Callow, P, Frielinghaus, H, Pipich, V, Prévost, S, Schreiber, F
格式: Journal article
语言:English
出版: 2012