Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score
<strong>Background</strong> Prostate cancer risk stratification using single-nucleotide polymorphisms (SNPs) demonstrates considerable promise in men of European, Asian, and African genetic ancestries, but there is still need for increased accuracy. We evaluated whether including additio...
Main Authors: | Huynh-Le, M, Karunamuni, R, Fan, CC, Neal, DE, Travis, RC, Mills, IG |
---|---|
Other Authors: | UKGPCS collaborators |
Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2022
|
Similar Items
-
Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer
by: Karunamuni, RA, et al.
Published: (2021) -
The effect of sample size on polygenic hazard models for prostate cancer
by: Karunamuni, RA, et al.
Published: (2020) -
Polygenic hazard score for prostate cancer risk stratification: validation in additional longitudinal cohorts
by: Tye, K, et al.
Published: (2019) -
Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry
by: Darst, BF, et al.
Published: (2023) -
Performance of African-ancestry-specific polygenic hazard score varies according to local ancestry in 8q24
by: Karunamuni, RA, et al.
Published: (2021)