Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score

Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score

<strong>Background</strong> Prostate cancer risk stratification using single-nucleotide polymorphisms (SNPs) demonstrates considerable promise in men of European, Asian, and African genetic ancestries, but there is still need for increased accuracy. We evaluated whether including additio...

书目详细资料
Main Authors:	Huynh-Le, M, Karunamuni, R, Fan, CC, Neal, DE, Travis, RC, Mills, IG
其他作者:	UKGPCS collaborators
格式:	Journal article
语言:	English
出版:	Springer Nature 2022

相似书籍

Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer
由: Karunamuni, RA, et al.
出版: (2021)

The effect of sample size on polygenic hazard models for prostate cancer
由: Karunamuni, RA, et al.
出版: (2020)

Polygenic hazard score for prostate cancer risk stratification: validation in additional longitudinal cohorts
由: Tye, K, et al.
出版: (2019)

Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry
由: Darst, BF, et al.
出版: (2023)

Performance of African-ancestry-specific polygenic hazard score varies according to local ancestry in 8q24
由: Karunamuni, RA, et al.
出版: (2021)

Polygenic hazard score is associated with prostate cancer in multi-ethnic populations
由: Huynh-Le, M, et al.
出版: (2021)

A genetic risk score to personalize prostate cancer screening, applied to population data
由: Huynh-Le, M-P, et al.
出版: (2020)

Polygenic transcriptome risk scores (PTRS) can improve portability of polygenic risk scores across ancestries
由: Yanyu Liang, et al.
出版: (2022-01-01)

African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer
由: Karunamuni, RA, et al.
出版: (2020)

Optimal strategies for learning multi-ancestry polygenic scores vary across traits
由: Brieuc Lehmann, et al.
出版: (2023-07-01)

On cross-ancestry cancer polygenic risk scores.
由: Lars G Fritsche, et al.
出版: (2021-09-01)

Polygenic hazard score is associated with prostate cancer in multi-ethnic populations
由: Minh-Phuong Huynh-Le, et al.
出版: (2021-02-01)

Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts.
由: Seibert, TM, et al.
出版: (2018)

Transferability of polygenic risk score among diverse ancestries
由: Xi Cheng, et al.
出版: (2023-08-01)

Benchmarking multi-ancestry prostate cancer polygenic risk scores in a real-world cohort.
由: Yajas Shah, et al.
出版: (2024-04-01)

Variable prediction accuracy of polygenic scores within an ancestry group
由: Hakhamanesh Mostafavi, et al.
出版: (2020-01-01)

Testing the generalizability of ancestry-specific polygenic risk scores to predict prostate cancer in sub-Saharan Africa
由: Michelle S. Kim, et al.
出版: (2022-09-01)

Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction
由: Kristia Yiangou, et al.
出版: (2024-12-01)

Polygenic prediction across populations is influenced by ancestry, genetic architecture, and methodology
由: Ying Wang, et al.
出版: (2023-10-01)

Demographic history mediates the effect of stratification on polygenic scores
由: Arslan A Zaidi, et al.
出版: (2020-11-01)

Performance of polygenic risk scores in screening, prediction, and risk stratification: secondary analysis of data in the Polygenic Score Catalog
由: Harry Hemingway, et al.
出版: (2023-07-01)

Analysis of ancestry-specific polygenic risk score and diet composition in type 2 diabetes.
由: Dale S Hardy, et al.
出版: (2023-01-01)

Evaluation of optimal methods and ancestries for calculating polygenic risk scores in East Asian population
由: Dong Jun Kim, et al.
出版: (2023-11-01)

Ancestry-specific polygenic risk scores are risk enhancers for clinical cardiovascular disease assessments
由: George B. Busby, et al.
出版: (2023-11-01)

Analysis of ancestry-specific polygenic risk score and diet composition in type 2 diabetes
由: Dale S. Hardy, et al.
出版: (2023-01-01)

Improving polygenic prediction with genetically inferred ancestry
由: Olivier Naret, et al.
出版: (2022-07-01)

Polygenic risk and hazard scores for Alzheimer's disease prediction
由: Leonenko, G, et al.
出版: (2019)

Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration
由: Tan, Chin Hong, et al.
出版: (2020)

Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
由: Itziar de Rojas, et al.
出版: (2021-06-01)

Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations
由: Fei Chen, et al.
出版: (2022-07-01)

PRState: Incorporating genetic ancestry in prostate cancer risk scores for men of African ancestry
由: Meghana S. Pagadala, et al.
出版: (2022-12-01)

A multi-ancestry genome-wide association study and evaluation of polygenic scores of LDL-C levels
由: Umm-Kulthum Ismail Umlai, et al.
出版: (2025-03-01)

Haplotype function score improves biological interpretation and cross-ancestry polygenic prediction of human complex traits
由: Weichen Song, et al.
出版: (2024-04-01)

Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations
由: Tian Ge, et al.
出版: (2022-06-01)

Prostate cancer polygenic risk score and prediction of lethal prostate cancer
由: Robert J. Klein, et al.
出版: (2022-04-01)

Polygenic risk scores across the extended psychosis spectrum
由: Lukasz Smigielski, et al.
出版: (2021-11-01)

P063: A second-generation polygenic risk score (PRS) based on genetic ancestry improves breast cancer (BC) risk prediction for all ancestries*
由: Timothy Simmons, et al.
出版: (2024-01-01)

Ancestry-aligned polygenic scores combined with conventional risk factors improve prediction of cardiometabolic outcomes in African populations
由: Michelle Kamp, et al.
出版: (2024-08-01)

Author Correction: Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
由: Itziar de Rojas, et al.
出版: (2023-02-01)

Impact of individual level uncertainty of lung cancer polygenic risk score (PRS) on risk stratification
由: Xinan Wang, et al.
出版: (2024-02-01)