Cardiac dysfunction and metabolic inflexibility in a mouse model of diabetes without dyslipidaemia
Diabetes is a well-established risk factor for heart disease leading to impaired cardiac function and a metabolic switch towards fatty acid usage. Here, we investigated if hyperglycaemia/hypoinsulinaemia in the absence of dyslipidaemia is sufficient to drive these changes, and if they can be reverse...
Main Authors: | Rohm, M, Savic, D, Ball, V, Curtis, M, Bonham, S, Fischer, R, Legrave, N, MacRae, J, Tyler, D, Ashcroft, F |
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Format: | Journal article |
Language: | English |
Published: |
American Diabetes Association
2018
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