Reprioritizing genetic associations in hit regions using LASSO-based resample model averaging.
Significance testing one SNP at a time has proven useful for identifying genomic regions that harbor variants affecting human disease. But after an initial genome scan has identified a "hit region" of association, single-locus approaches can falter. Local linkage disequilibrium (LD) can ma...
| Автори: | , , , |
|---|---|
| Формат: | Journal article |
| Мова: | English |
| Опубліковано: |
2012
|