Outcome of invasive pneumococcal disease: a UK based study. Oxford Pneumococcal Surveillance Group.
METHODS: The records of 106 children aged less than 5 years with invasive disease caused by Streptococcus pneumoniae were reviewed. RESULTS: The clinical manifestations were meningitis (37%), upper respiratory tract infection (24%), pneumonia (19%), and occult bacteraemia (18%). One child died and s...
| Main Authors: | , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2000
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| _version_ | 1826298976444350464 |
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| author | Shackley, F Knox, K Morris, J Crook, D Griffiths, D Mayon-White, R George, R Willocks, L Moxon, E |
| author_facet | Shackley, F Knox, K Morris, J Crook, D Griffiths, D Mayon-White, R George, R Willocks, L Moxon, E |
| author_sort | Shackley, F |
| collection | OXFORD |
| description | METHODS: The records of 106 children aged less than 5 years with invasive disease caused by Streptococcus pneumoniae were reviewed. RESULTS: The clinical manifestations were meningitis (37%), upper respiratory tract infection (24%), pneumonia (19%), and occult bacteraemia (18%). One child died and seven had persisting neurological impairment. Five serotypes caused 83% of disease and 92% of the serotypes are included in the seven valent conjugate vaccines which are undergoing trials. CONCLUSIONS: These data suggest that S pneumoniae infection is associated with a low case fatality rate but substantial morbidity in the UK. |
| first_indexed | 2024-03-07T04:54:55Z |
| format | Journal article |
| id | oxford-uuid:d63fd664-8278-4910-899c-b14e20a07b82 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:54:55Z |
| publishDate | 2000 |
| record_format | dspace |
| spelling | oxford-uuid:d63fd664-8278-4910-899c-b14e20a07b822022-03-27T08:32:10ZOutcome of invasive pneumococcal disease: a UK based study. Oxford Pneumococcal Surveillance Group.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d63fd664-8278-4910-899c-b14e20a07b82EnglishSymplectic Elements at Oxford2000Shackley, FKnox, KMorris, JCrook, DGriffiths, DMayon-White, RGeorge, RWillocks, LMoxon, EMETHODS: The records of 106 children aged less than 5 years with invasive disease caused by Streptococcus pneumoniae were reviewed. RESULTS: The clinical manifestations were meningitis (37%), upper respiratory tract infection (24%), pneumonia (19%), and occult bacteraemia (18%). One child died and seven had persisting neurological impairment. Five serotypes caused 83% of disease and 92% of the serotypes are included in the seven valent conjugate vaccines which are undergoing trials. CONCLUSIONS: These data suggest that S pneumoniae infection is associated with a low case fatality rate but substantial morbidity in the UK. |
| spellingShingle | Shackley, F Knox, K Morris, J Crook, D Griffiths, D Mayon-White, R George, R Willocks, L Moxon, E Outcome of invasive pneumococcal disease: a UK based study. Oxford Pneumococcal Surveillance Group. |
| title | Outcome of invasive pneumococcal disease: a UK based study. Oxford Pneumococcal Surveillance Group. |
| title_full | Outcome of invasive pneumococcal disease: a UK based study. Oxford Pneumococcal Surveillance Group. |
| title_fullStr | Outcome of invasive pneumococcal disease: a UK based study. Oxford Pneumococcal Surveillance Group. |
| title_full_unstemmed | Outcome of invasive pneumococcal disease: a UK based study. Oxford Pneumococcal Surveillance Group. |
| title_short | Outcome of invasive pneumococcal disease: a UK based study. Oxford Pneumococcal Surveillance Group. |
| title_sort | outcome of invasive pneumococcal disease a uk based study oxford pneumococcal surveillance group |
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