Prevalence of malaria in native and transmigrant populations. Effects of age and history of exposure.

A malaria prevalence study was performed in a village in Irian Jaya, Indonesia, that contains a population of people who have been exposed lifelong to hyperendemic malaria and another population of people who had arrived 18 months previously from areas of very low endemicity. Mean spleen sizes corre...

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Main Authors: Jones, T, Baird, J, Basri, H, Purnomo, Danudirgo, E
Format: Journal article
Language:English
Published: 1991
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author Jones, T
Baird, J
Basri, H
Purnomo
Danudirgo, E
author_facet Jones, T
Baird, J
Basri, H
Purnomo
Danudirgo, E
author_sort Jones, T
collection OXFORD
description A malaria prevalence study was performed in a village in Irian Jaya, Indonesia, that contains a population of people who have been exposed lifelong to hyperendemic malaria and another population of people who had arrived 18 months previously from areas of very low endemicity. Mean spleen sizes correlated positively with prevalence of malaria, not resistance to it. Prevalence of sexual and asexual blood stage parasites was higher in transmigrants than in the natives. The data also show that clinical resistance to malaria in this part of the world includes resistance to Plasmodium falciparum gametocytemia and that this is not the passive byproduct of a reduction in asexual parasites. This indicates that the introduction of native people into a populated malarious area will increase the percent of gametocyte carriers and may, thereby, increase the entomologic inoculation rate.
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spelling oxford-uuid:d646ce4b-d632-44d2-bf34-20c0932d6f972022-03-27T08:32:21ZPrevalence of malaria in native and transmigrant populations. Effects of age and history of exposure.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d646ce4b-d632-44d2-bf34-20c0932d6f97EnglishSymplectic Elements at Oxford1991Jones, TBaird, JBasri, HPurnomoDanudirgo, EA malaria prevalence study was performed in a village in Irian Jaya, Indonesia, that contains a population of people who have been exposed lifelong to hyperendemic malaria and another population of people who had arrived 18 months previously from areas of very low endemicity. Mean spleen sizes correlated positively with prevalence of malaria, not resistance to it. Prevalence of sexual and asexual blood stage parasites was higher in transmigrants than in the natives. The data also show that clinical resistance to malaria in this part of the world includes resistance to Plasmodium falciparum gametocytemia and that this is not the passive byproduct of a reduction in asexual parasites. This indicates that the introduction of native people into a populated malarious area will increase the percent of gametocyte carriers and may, thereby, increase the entomologic inoculation rate.
spellingShingle Jones, T
Baird, J
Basri, H
Purnomo
Danudirgo, E
Prevalence of malaria in native and transmigrant populations. Effects of age and history of exposure.
title Prevalence of malaria in native and transmigrant populations. Effects of age and history of exposure.
title_full Prevalence of malaria in native and transmigrant populations. Effects of age and history of exposure.
title_fullStr Prevalence of malaria in native and transmigrant populations. Effects of age and history of exposure.
title_full_unstemmed Prevalence of malaria in native and transmigrant populations. Effects of age and history of exposure.
title_short Prevalence of malaria in native and transmigrant populations. Effects of age and history of exposure.
title_sort prevalence of malaria in native and transmigrant populations effects of age and history of exposure
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AT bairdj prevalenceofmalariainnativeandtransmigrantpopulationseffectsofageandhistoryofexposure
AT basrih prevalenceofmalariainnativeandtransmigrantpopulationseffectsofageandhistoryofexposure
AT purnomo prevalenceofmalariainnativeandtransmigrantpopulationseffectsofageandhistoryofexposure
AT danudirgoe prevalenceofmalariainnativeandtransmigrantpopulationseffectsofageandhistoryofexposure