The actin cytoskeleton modulates the activation of invariant NKT cells by segregating CD1d nanoclusters on antigen presenting cells

Invariant natural killer T (iNKT) cells recognize endogenous and exogenous lipid antigens presented in the context of CD1d molecules. The ability of iNKT cells to recognize endogenous antigens represents a distinct immune recognition strategy, which underscores the constitutive memory phenotype of i...

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Detalhes bibliográficos
Principais autores: Cerundolo, V, Salio, M, Shepherd, D, Torreno-Pina, J, Manzo, C, Aichinger, M, Oddone, A, Bestra, G, Garcia-Parajo, M
Formato: Journal article
Publicado em: National Academy of Sciences 2016