The role of CD4+ T-cell subsets in determining transplantation rejection or tolerance.

Peripheral tolerance to allogeneic organ grafts can be induced in rodents by treating with non-depleting CD4 and CD8 monoclonal antibodies. This tolerance is maintained by CD4+ T cells with a potent capacity to induce tolerance in further cohorts of T cells (i.e. infectious tolerance). We have clone...

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Hlavní autoři: Zelenika, D, Adams, E, Humm, S, Lin, C, Waldmann, H, Cobbold, S
Médium: Journal article
Jazyk:English
Vydáno: 2001