What is the minimal length of calcium pentosan polysulfate that is able to block aggrecan breakdown in cartilage?

What is the minimal length of calcium pentosan polysulfate that is able to block aggrecan breakdown in cartilage?

Manylion Llyfryddiaeth
Prif Awduron:	Troeberg, L, Mulloy, B, Nagase, H
Fformat:	Journal article
Cyhoeddwyd:	2009

Eitemau Tebyg

Calcium pentosan polysulfate is a multi-functional aggrecanase inhibitor that enhances interaction with endogenous TIMP-3 in cartilage
gan: Troeberg, L, et al.
Cyhoeddwyd: (2009)

Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases.
gan: Troeberg, L, et al.
Cyhoeddwyd: (2008)

Calcium pentosan polysulfate increases affinity between aggrecanases (ADAMTS-4 and-5) and TIMP-3 by a conformational change
gan: Troeberg, L, et al.
Cyhoeddwyd: (2010)

Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex
gan: Troeberg, L, et al.
Cyhoeddwyd: (2012)

Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex.
gan: Troeberg, L, et al.
Cyhoeddwyd: (2012)

Aggrecan breakdown in cartilage induced by proteolytic fragments of fibronectin: implications in osteoarthritis
gan: Nagase, H
Cyhoeddwyd: (2009)

Pentosan Polysulfate Maculopathy—Prescribers Should Be Aware
gan: Yusuf, IH, et al.
Cyhoeddwyd: (2020)

Potential Anti-SARS-CoV-2 Activity of Pentosan Polysulfate and Mucopolysaccharide Polysulfate
gan: Fuming Zhang, et al.
Cyhoeddwyd: (2022-02-01)

Potentiation of carbon tetrachloride hepatotoxicity by pentosan polysulfate in rats
gan: Zim M.C.A., et al.
Cyhoeddwyd: (2002-01-01)

Pentosan Polysulfate Affords Pleotropic Protection to Multiple Cells and Tissues
gan: Margaret M. Smith, et al.
Cyhoeddwyd: (2023-03-01)

Use of Pentosan Polysulfate in the Local Treatment of Reactive Arthritis in Children
gan: O.A. Danylov, et al.
Cyhoeddwyd: (2016-05-01)

Type 3 macular neovascularization in a patient with pentosan polysulfate maculopathy
gan: Elodie Bousquet, et al.
Cyhoeddwyd: (2023-03-01)

Effectiveness of oral pentosan polysulfate in painful bladder syndrome: Is it worth the cost?
gan: Devdatt Purushottam Palnitkar, et al.
Cyhoeddwyd: (2021-01-01)

Maculopathy Secondary to Pentosan Polysulfate Use: A Single-Center Experience
gan: Kalbag NS, et al.
Cyhoeddwyd: (2021-02-01)

Involvement of ADAMTS5 and hyaluronidase in aggrecan degradation and release from OSM-stimulated cartilage.
gan: Durigova, M, et al.
Cyhoeddwyd: (2011)

Involvement of ADAMTS5 and hyaluronidase in aggrecan degradation and release from OSM-stimulated cartilage
gan: M Durigova, et al.
Cyhoeddwyd: (2011-01-01)

Advanced pentosan polysulfate sodium maculopathy with low cumulative exposure and hydroxychloroquine use
gan: Elena Flester, et al.
Cyhoeddwyd: (2024-12-01)

Acute and severe haemorrhage following pentosan polysulfate injection in a Cornish Rex
gan: Miranda X Tong, et al.
Cyhoeddwyd: (2021-11-01)

Pentosan Polysulfate Sodium-Associated Pigmentary Retinopathy: Risk Factors and Fundus Findings
gan: Leung EH, et al.
Cyhoeddwyd: (2021-12-01)

Efficacy of pentosan polysulfate in in vitro models of lysosomal storage disorders: Fabry and Gaucher Disease.
gan: Andrea N Crivaro, et al.
Cyhoeddwyd: (2019-01-01)

Isolation of fibronectin fragments that induce aggrecan degradation in cartilage
gan: Sofat, N, et al.
Cyhoeddwyd: (2006)

Fibronectin fragments induce aggrecan degradation in human cartilage and are increased in osteoarthritic cartilage
gan: Sofat, N, et al.
Cyhoeddwyd: (2007)

In-depth structural characterization of pentosan polysulfate sodium complex drug using orthogonal analytical tools
gan: Alekseeva, Anna, et al.
Cyhoeddwyd: (2021)

In-depth structural characterization of pentosan polysulfate sodium complex drug using orthogonal analytical tools
gan: Alekseeva, Anna, et al.
Cyhoeddwyd: (2022)

Retrospective study of incidence/prevalence of pigmentary maculopathy and retinopathy in patients receiving pentosan polysulfate sodium.
gan: Zhong Yuan, et al.
Cyhoeddwyd: (2025-01-01)

An unusual case of rapid resolution of bilateral vitelliform deposits after discontinuation of pentosan polysulfate sodium
gan: Fritz Gerald P. Kalaw, et al.
Cyhoeddwyd: (2023-12-01)

Xylan Prebiotics and the Gut Microbiome Promote Health and Wellbeing: Potential Novel Roles for Pentosan Polysulfate
gan: Margaret M. Smith, et al.
Cyhoeddwyd: (2022-09-01)

Screening practices and risk assessment for maculopathy in pentosan polysulfate users across different exposure levels
gan: Hyeon Yoon Kwon, et al.
Cyhoeddwyd: (2024-05-01)

JNK2 controls aggrecan degradation in murine articular cartilage and the development of experimental osteoarthritis.
gan: Ismail, H, et al.
Cyhoeddwyd: (2015)

Identifying synovial tissue-derived catabolic factors of cartilage aggrecan
gan: Rana, F, et al.
Cyhoeddwyd: (2013)

Apolipoprotein A-1 is a novel inducer of aggrecan breakdown in cultured articular cartilage
gan: Didangelos, A, et al.
Cyhoeddwyd: (2009)

Aggrecan structure in amphibian cartilage
gan: Covizi D.Z., et al.
Cyhoeddwyd: (2000-01-01)

Sentiments of Individuals with Interstitial Cystitis/Bladder Pain Syndrome Toward Pentosan Polysulfate Sodium: Infodemiology Study
gan: Yulin Hswen, et al.
Cyhoeddwyd: (2025-01-01)

Pigmentary Maculopathy in Interstitial Cystitis/Bladder Pain Syndrome Treated with Oral Pentosan Polysulfate: A Review
gan: Richard Parkinson, et al.
Cyhoeddwyd: (2022-09-01)

Inhibitory effects of sodium pentosan polysulfate on formation and function of osteoclasts derived from canine bone marrow
gan: H. M. Suranji Wijekoon, et al.
Cyhoeddwyd: (2018-05-01)

Probing nanomechanics of aggrecan and the aggrecan-rich pericellular matrix of chondrocytes in cartilage
gan: Ng, Laurel Jean
Cyhoeddwyd: (2006)

Transient Postoperative Hemorrhage from Elbow Arthroscopy Portals following Intra-Articular Pentosan Polysulfate Sodium Injection
gan: Lindsay A. Parker, et al.
Cyhoeddwyd: (2022-01-01)

Identification of Patients with Pentosan Polysulfate Sodium-Associated Maculopathy through Screening of the Electronic Medical Record at an Academic Center
gan: Kendall Higgins, et al.
Cyhoeddwyd: (2020-01-01)

The effect of pentosan polysulfate sodium for improving dyslipidaemia and knee pain in people with knee osteoarthritis: A pilot study
gan: Xiaoqian Liu, et al.
Cyhoeddwyd: (2023-06-01)

Role of oral pentosan polysulfate in Bacillus Calmette–Guérin therapy in patients with non-muscle-invasive bladder cancer
gan: Ho Yeon Lee, et al.
Cyhoeddwyd: (2022-09-01)