Processing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation.

Processing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation.

Clustered DNA damage sites, in which two or more lesions are formed within a few helical turns of the DNA after passage of a single radiation track, are signatures of DNA modifications induced by ionizing radiation in mammalian cells. Mutant hamster cells (xrs-5), deficient in non-homologous end joi...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Gulston, M, de Lara, C, Jenner, T, Davis, E, O'Neill, P
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	2004

Ижил төстэй зүйлс

Induction of persistent double strand breaks following multiphoton irradiation of cycling and G1-arrested mammalian cells-replication-induced double strand breaks.
-н: Harper, J, зэрэг
Хэвлэсэн: (2008)

Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage.
-н: Eccles, L, зэрэг
Хэвлэсэн: (2010)

Clustered DNA damage induced by gamma radiation in human fibroblasts (HF19), hamster (V79-4) cells and plasmid DNA is revealed as Fpg and Nth sensitive sites.
-н: Gulston, M, зэрэг
Хэвлэсэн: (2002)

Chemical aspects of clustered DNA damage induction by ionising radiation.
-н: Lomax, M, зэрэг
Хэвлэсэн: (2002)

Dependence of the yield of DNA double-strand breaks in Chinese hamster V79-4 cells on the photon energy of ultrasoft X rays.
-н: de Lara, C, зэрэг
Хэвлэсэн: (2001)

Effects of hydration on the induction of strand breaks, base lesions, and clustered damage in DNA films by alpha-radiation
-н: Yokoya, A, зэрэг
Хэвлэсэн: (2003)

Enhanced DNA double strand break repair triggered by microbeam irradiation induced cytoplasmic damage
-н: Teruaki Konishi, зэрэг
Хэвлэсэн: (2018-01-01)

Removal of heat-sensitive clustered damaged DNA sites is independent of double-strand break repair.
-н: Andris Abramenkovs, зэрэг
Хэвлэсэн: (2018-01-01)

Interplay of two major repair pathways in the processing of complex double-strand DNA breaks.
-н: Dobbs, T, зэрэг
Хэвлэсэн: (2008)

Surrogates for the removal by ozonation of the cytotoxicity and DNA double-strand break effects of wastewater on mammalian cells
-н: Ye Du, зэрэг
Хэвлэсэн: (2020-02-01)

Quantitative measurement and modeling of the DNA damage signaling network : DNA double-strand breaks
-н: Tentner, Andrea R. (Andrea Ruth)
Хэвлэсэн: (2011)

Induction of DNA strand breaks, base lesions and clustered damage sites in hydrated plasmid DNA films by ultrasoft X rays around the phosphorus K edge.
-н: Yokoya, A, зэрэг
Хэвлэсэн: (2009)

LET dependence of the yield of single-, double-strand breaks and base lesions in fully hydrated plasmid DNA films by 4He(2+) ion irradiation.
-н: Urushibara, A, зэрэг
Хэвлэсэн: (2008)

Pathway utilization in response to a site-specific DNA double-strand break in fission yeast.
-н: Prudden, J, зэрэг
Хэвлэсэн: (2003)

Physiological Roles of DNA Double-Strand Breaks
-н: Farhaan A. Khan, зэрэг
Хэвлэсэн: (2017-01-01)

Repair of DNA Double-Strand Breaks in Heterochromatin
-н: Felicity Z. Watts
Хэвлэсэн: (2016-12-01)

DNA double-strand break repair in mammals
-н: Monica Pandey, зэрэг
Хэвлэсэн: (2017-01-01)

Hyperactivation of DNA-PK by double-strand break mimicking molecules disorganizes DNA damage response.
-н: Maria Quanz, зэрэг
Хэвлэсэн: (2009-07-01)

Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae.
-н: Yong Yang, зэрэг
Хэвлэсэн: (2008-11-01)

Human RecQ Helicases in DNA Double-Strand Break Repair
-н: Huiming Lu, зэрэг
Хэвлэсэн: (2021-02-01)

Factors affecting double-strand break-induced homologous recombination in mammalian cells
-н: Christophe Perez, зэрэг
Хэвлэсэн: (2005-07-01)

Real estate in the DNA damage response: Ubiquitin and SUMO ligases home in on DNA double-strand breaks
-н: Nico P. Dantuma, зэрэг
Хэвлэсэн: (2016-04-01)

Phase separation in DNA double-strand break response
-н: Huan-Lei Liu, зэрэг
Хэвлэсэн: (2024-12-01)

DNA double-strand breaks in immunoinflammatory rheumatic diseases
-н: A. S. Avdeeva, зэрэг
Хэвлэсэн: (2023-08-01)

Mechanical evolution of DNA double-strand breaks in the nucleosome.
-н: Fabrizio Cleri, зэрэг
Хэвлэсэн: (2018-06-01)

The Chromatin Response to Double-Strand DNA Breaks and Their Repair
-н: Radoslav Aleksandrov, зэрэг
Хэвлэсэн: (2020-08-01)

Contribution of base lesions to radiation-induced clustered DNA damage: implication for models of radiation response.
-н: Jenner, T, зэрэг
Хэвлэсэн: (2001)

Excess single-stranded DNA inhibits meiotic double-strand break repair.
-н: Rebecca Johnson, зэрэг
Хэвлэсэн: (2007-11-01)

Base excision repair processing of abasic site/single-strand break lesions within clustered damage sites associated with XRCC1 deficiency.
-н: Mourgues, S, зэрэг
Хэвлэсэн: (2007)

Efficiency of repair of an abasic site within DNA clustered damage sites by mammalian cell nuclear extracts.
-н: Lomax, M, зэрэг
Хэвлэсэн: (2004)

8-OxoG retards the activity of the ligase III/XRCC1 complex during the repair of a single-strand break, when present within a clustered DNA damage site.
-н: Lomax, M, зэрэг
Хэвлэсэн: (2004)

DNA Double-Strand Breaks: A Double-Edged Sword for Trypanosomatids
-н: Marcelo Santos da Silva
Хэвлэсэн: (2021-04-01)

Constitutional Chromothripsis Rearrangements Involve Clustered Double-Stranded DNA Breaks and Nonhomologous Repair Mechanisms
-н: Wigard P. Kloosterman, зэрэг
Хэвлэсэн: (2012-06-01)

DNA double-strand break end synapsis by DNA loop extrusion
-н: Jin H. Yang, зэрэг
Хэвлэсэн: (2023-04-01)

The role of DNA polymerase I in tolerating single-strand breaks generated at clustered DNA damage in Escherichia coli
-н: Naoya Shikazono, зэрэг
Хэвлэсэн: (2024-08-01)

Valproic Acid-Mediated Reduction of DNA Double-Strand Break Reparation Capacity of Irradiated MCF-7 Cells
-н: Ahmad yarmohamadi, зэрэг
Хэвлэсэн: (2016-12-01)

Effect of hydration on the induction of strand breaks and base lesions in plasmid DNA films by gamma-radiation.
-н: Yokoya, A, зэрэг
Хэвлэсэн: (2002)

HIV Vpr Modulates the Host DNA Damage Response at Two Independent Steps to Damage DNA and Repress Double-Strand DNA Break Repair
-н: Donna Li, зэрэг
Хэвлэсэн: (2020-08-01)

DNA double-strand break repair pathway choice in Dictyostelium.
-н: Hsu, D, зэрэг
Хэвлэсэн: (2011)

Investigating DNA double-strand break repair in Dictyostelium discoideum
-н: Couto, C
Хэвлэсэн: (2011)