Processing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation.

Processing of clustered DNA damage generates additional double-strand breaks in mammalian cells post-irradiation.

Clustered DNA damage sites, in which two or more lesions are formed within a few helical turns of the DNA after passage of a single radiation track, are signatures of DNA modifications induced by ionizing radiation in mammalian cells. Mutant hamster cells (xrs-5), deficient in non-homologous end joi...

Bibliografske podrobnosti
Main Authors:	Gulston, M, de Lara, C, Jenner, T, Davis, E, O'Neill, P
Format:	Journal article
Jezik:	English
Izdano:	2004

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