Synthesis of oligomers of tetrahydrofuran amino acids: furanose carbopeptoids
An acid catalysed ring rearrangement of a triflate derivative of D-mannono-γ-lactone 6 is the key step in the synthesis of the C-glycosyl sugar amino acid derivatives 3 and 4, examples of carbohydrate amino acid building blocks with specific conformational preferences suitable for incorporation into...
প্রধান লেখক: | , , , , |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
1998
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_version_ | 1826299045098815488 |
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author | Smith, M Long, D Marquess, D Claridge, T Fleet, G |
author_facet | Smith, M Long, D Marquess, D Claridge, T Fleet, G |
author_sort | Smith, M |
collection | OXFORD |
description | An acid catalysed ring rearrangement of a triflate derivative of D-mannono-γ-lactone 6 is the key step in the synthesis of the C-glycosyl sugar amino acid derivatives 3 and 4, examples of carbohydrate amino acid building blocks with specific conformational preferences suitable for incorporation into combinatorial amide libraries; homo-oligomerisation via solution phase coupling procedures affords furanose carbopeptoids 1 which adopt novel solution state secondary structures. |
first_indexed | 2024-03-07T04:55:55Z |
format | Journal article |
id | oxford-uuid:d699a726-77db-4180-9ff2-3d7f216d1bc3 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T04:55:55Z |
publishDate | 1998 |
record_format | dspace |
spelling | oxford-uuid:d699a726-77db-4180-9ff2-3d7f216d1bc32022-03-27T08:34:43ZSynthesis of oligomers of tetrahydrofuran amino acids: furanose carbopeptoidsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d699a726-77db-4180-9ff2-3d7f216d1bc3EnglishSymplectic Elements at Oxford1998Smith, MLong, DMarquess, DClaridge, TFleet, GAn acid catalysed ring rearrangement of a triflate derivative of D-mannono-γ-lactone 6 is the key step in the synthesis of the C-glycosyl sugar amino acid derivatives 3 and 4, examples of carbohydrate amino acid building blocks with specific conformational preferences suitable for incorporation into combinatorial amide libraries; homo-oligomerisation via solution phase coupling procedures affords furanose carbopeptoids 1 which adopt novel solution state secondary structures. |
spellingShingle | Smith, M Long, D Marquess, D Claridge, T Fleet, G Synthesis of oligomers of tetrahydrofuran amino acids: furanose carbopeptoids |
title | Synthesis of oligomers of tetrahydrofuran amino acids: furanose carbopeptoids |
title_full | Synthesis of oligomers of tetrahydrofuran amino acids: furanose carbopeptoids |
title_fullStr | Synthesis of oligomers of tetrahydrofuran amino acids: furanose carbopeptoids |
title_full_unstemmed | Synthesis of oligomers of tetrahydrofuran amino acids: furanose carbopeptoids |
title_short | Synthesis of oligomers of tetrahydrofuran amino acids: furanose carbopeptoids |
title_sort | synthesis of oligomers of tetrahydrofuran amino acids furanose carbopeptoids |
work_keys_str_mv | AT smithm synthesisofoligomersoftetrahydrofuranaminoacidsfuranosecarbopeptoids AT longd synthesisofoligomersoftetrahydrofuranaminoacidsfuranosecarbopeptoids AT marquessd synthesisofoligomersoftetrahydrofuranaminoacidsfuranosecarbopeptoids AT claridget synthesisofoligomersoftetrahydrofuranaminoacidsfuranosecarbopeptoids AT fleetg synthesisofoligomersoftetrahydrofuranaminoacidsfuranosecarbopeptoids |