Improved prediction of Bovine Leucocyte Antigens (BoLA) presented ligands by use of mass-spectrometry-determined ligand and in vitro binding data

Peptide binding to MHC class I molecules is the single most selective step in antigen presentation and the strongest single correlate to peptide cellular immunogenicity. The cost of experimentally characterizing the rules of peptide presentation for a given MHC-I molecule is extensive, and predictor...

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Detalhes bibliográficos
Main Authors: Nielsen, M, Connelley, T, Ternette, N
Formato: Journal article
Idioma:English
Publicado em: American Chemical Society 2017