Advances in polycyclization cascades in natural product synthesis
Cascade reactions (also known as domino reactions) are arguably the most powerful means to achieve the construction of multiple ring systems in a single step. In this Tutorial Review, highlights in cascade polycyclizations applied to natural product syntheses over the last five years are discussed,...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Royal Society of Chemistry
2020
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| _version_ | 1797097482803478528 |
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| author | Jiang, Y McNamee, RE Smith, PJ Sozanschi, A Tong, Z Anderson, EA |
| author_facet | Jiang, Y McNamee, RE Smith, PJ Sozanschi, A Tong, Z Anderson, EA |
| author_sort | Jiang, Y |
| collection | OXFORD |
| description | Cascade reactions (also known as domino reactions) are arguably the most powerful means to achieve the construction of multiple ring systems in a single step. In this Tutorial Review, highlights in cascade polycyclizations applied to natural product syntheses over the last five years are discussed, including pericyclic, ionic, metal-catalyzed, organocatalytic, and radical processes. Significant developments in each of these fields that have advanced the state-of-the-art are a particular focus, including photochemical and electrochemical methods, novel biomimetic routes, and enantioselective cascades. |
| first_indexed | 2024-03-07T04:56:09Z |
| format | Journal article |
| id | oxford-uuid:d6abaecc-6d17-4d02-82e9-169c7aa5b957 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:56:09Z |
| publishDate | 2020 |
| publisher | Royal Society of Chemistry |
| record_format | dspace |
| spelling | oxford-uuid:d6abaecc-6d17-4d02-82e9-169c7aa5b9572022-03-27T08:35:14ZAdvances in polycyclization cascades in natural product synthesisJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d6abaecc-6d17-4d02-82e9-169c7aa5b957EnglishSymplectic ElementsRoyal Society of Chemistry2020Jiang, YMcNamee, RESmith, PJSozanschi, ATong, ZAnderson, EACascade reactions (also known as domino reactions) are arguably the most powerful means to achieve the construction of multiple ring systems in a single step. In this Tutorial Review, highlights in cascade polycyclizations applied to natural product syntheses over the last five years are discussed, including pericyclic, ionic, metal-catalyzed, organocatalytic, and radical processes. Significant developments in each of these fields that have advanced the state-of-the-art are a particular focus, including photochemical and electrochemical methods, novel biomimetic routes, and enantioselective cascades. |
| spellingShingle | Jiang, Y McNamee, RE Smith, PJ Sozanschi, A Tong, Z Anderson, EA Advances in polycyclization cascades in natural product synthesis |
| title | Advances in polycyclization cascades in natural product synthesis |
| title_full | Advances in polycyclization cascades in natural product synthesis |
| title_fullStr | Advances in polycyclization cascades in natural product synthesis |
| title_full_unstemmed | Advances in polycyclization cascades in natural product synthesis |
| title_short | Advances in polycyclization cascades in natural product synthesis |
| title_sort | advances in polycyclization cascades in natural product synthesis |
| work_keys_str_mv | AT jiangy advancesinpolycyclizationcascadesinnaturalproductsynthesis AT mcnameere advancesinpolycyclizationcascadesinnaturalproductsynthesis AT smithpj advancesinpolycyclizationcascadesinnaturalproductsynthesis AT sozanschia advancesinpolycyclizationcascadesinnaturalproductsynthesis AT tongz advancesinpolycyclizationcascadesinnaturalproductsynthesis AT andersonea advancesinpolycyclizationcascadesinnaturalproductsynthesis |