Single-cell profiling of lineage determining transcription factors in antigen-specific CD4+ T cells reveals unexpected complexity in recall responses during immune reconstitution
Recent studies of protein and gene expression at the single-cell level have revealed that the memory T-cell compartment is more heterogeneous than previously acknowledged. Identifying different T helper subsets involved in memory responses at the single-cell level is thus necessary to understand the...
Autors principals: | Phetsouphanh, C, Xu, Y, Munier, M, Zaunders, J, Kelleher, A |
---|---|
Format: | Journal article |
Idioma: | English |
Publicat: |
Wiley
2017
|
Ítems similars
-
Characterization of transcription factor phenotypes within antigen-specific CD4+ T cells using qualitative multiplex single-cell RT-PCR.
per: Chansavath Phetsouphanh, et al.
Publicat: (2013-01-01) -
Editorial: Cytotoxic CD4+ T cells in viral infections
per: Phetsouphanh, C, et al.
Publicat: (2017) -
23 Knockdown of CCR5 expression in antigen-specific cytotoxic CD4 T cells
per: John Zaunders, et al.
Publicat: (2017-07-01) -
Editorial: Cytotoxic CD4+ T Cells in Viral Infections
per: Chansavath Phetsouphanh, et al.
Publicat: (2017-12-01) -
CD4 T cells mediate both positive and negative regulation of the immune response to HIV infection: complex role of T follicular helper cells and Regulatory T cells in pathogenesis
per: Chansavath ePhetsouphanh, et al.
Publicat: (2015-01-01)