Single-cell profiling of lineage determining transcription factors in antigen-specific CD4+ T cells reveals unexpected complexity in recall responses during immune reconstitution

Recent studies of protein and gene expression at the single-cell level have revealed that the memory T-cell compartment is more heterogeneous than previously acknowledged. Identifying different T helper subsets involved in memory responses at the single-cell level is thus necessary to understand the...

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Detalles Bibliográficos
Autores principales: Phetsouphanh, C, Xu, Y, Munier, M, Zaunders, J, Kelleher, A
Formato: Journal article
Lenguaje:English
Publicado: Wiley 2017