Identification of the (183)RWTNNFREY(191) region as a critical segment of matrix metalloproteinase 1 for the expression of collagenolytic activity.

Identification of the (183)RWTNNFREY(191) region as a critical segment of matrix metalloproteinase 1 for the expression of collagenolytic activity.

Matrix metalloproteinase 1 (MMP-1) cleaves types I, II, and III collagen triple helices into (3/4) and (1/4) fragments. To understand the structural elements responsible for this activity, various lengths of MMP-1 segments have been introduced into MMP-3 (stromelysin 1) starting from the C-terminal...

תיאור מלא

מידע ביבליוגרפי
Main Authors:	Chung, L, Shimokawa, K, Dinakarpandian, D, Grams, F, Fields, G, Nagase, H
פורמט:	Journal article
שפה:	English
יצא לאור:	2000

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