EGAD! There is an ERAD doppelganger in the Golgi
Disposal of membrane proteins in the late secretory pathway is thought to be exclusively facilitated by ESCRT‐dependent lysosomal degradation. In this issue of The EMBO Journal, Schmidt et al define a previously uncharacterized endosome and Golgi‐associated degradation (EGAD) pathway. This pathway,...
| Päätekijät: | , |
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| Aineistotyyppi: | Journal article |
| Kieli: | English |
| Julkaistu: |
EMBO Press
2019
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| _version_ | 1826299084046073856 |
|---|---|
| author | Fonseca, D Carvalho, P |
| author_facet | Fonseca, D Carvalho, P |
| author_sort | Fonseca, D |
| collection | OXFORD |
| description | Disposal of membrane proteins in the late secretory pathway is thought to be exclusively facilitated by ESCRT‐dependent lysosomal degradation. In this issue of The EMBO Journal, Schmidt et al define a previously uncharacterized endosome and Golgi‐associated degradation (EGAD) pathway. This pathway, which has remarkable similarities to ERAD in the endoplasmic reticulum, operates in post‐ER organelles via the proteasome and contributes to lipid homeostasis in eukaryotic cells. |
| first_indexed | 2024-03-07T04:56:31Z |
| format | Journal article |
| id | oxford-uuid:d6cad8fb-149c-42e3-be7e-116861dae711 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:56:31Z |
| publishDate | 2019 |
| publisher | EMBO Press |
| record_format | dspace |
| spelling | oxford-uuid:d6cad8fb-149c-42e3-be7e-116861dae7112022-03-27T08:36:14ZEGAD! There is an ERAD doppelganger in the GolgiJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d6cad8fb-149c-42e3-be7e-116861dae711EnglishSymplectic Elements at OxfordEMBO Press2019Fonseca, DCarvalho, PDisposal of membrane proteins in the late secretory pathway is thought to be exclusively facilitated by ESCRT‐dependent lysosomal degradation. In this issue of The EMBO Journal, Schmidt et al define a previously uncharacterized endosome and Golgi‐associated degradation (EGAD) pathway. This pathway, which has remarkable similarities to ERAD in the endoplasmic reticulum, operates in post‐ER organelles via the proteasome and contributes to lipid homeostasis in eukaryotic cells. |
| spellingShingle | Fonseca, D Carvalho, P EGAD! There is an ERAD doppelganger in the Golgi |
| title | EGAD! There is an ERAD doppelganger in the Golgi |
| title_full | EGAD! There is an ERAD doppelganger in the Golgi |
| title_fullStr | EGAD! There is an ERAD doppelganger in the Golgi |
| title_full_unstemmed | EGAD! There is an ERAD doppelganger in the Golgi |
| title_short | EGAD! There is an ERAD doppelganger in the Golgi |
| title_sort | egad there is an erad doppelganger in the golgi |
| work_keys_str_mv | AT fonsecad egadthereisaneraddoppelgangerinthegolgi AT carvalhop egadthereisaneraddoppelgangerinthegolgi |