BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma

BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma

<p><strong>Background and Aims</strong></p> The dismal prognosis of pancreatic ductal adenocarcinoma (PDAC) is linked to the presence of pancreatic cancer stem-like cells (CSCs) that respond poorly to current chemotherapy regimens. The epigenetic mechanisms regulating CSCs ar...

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Main Authors: Feng, Y, Cai, L, Pook, M, Liu, F, Chang, C-H, Mouti, MA, Nibhani, R, Militi, S, Dunford, J, Philpott, M, Fan, Y, Fan, G-C, Liu, Q, Qi, J, Wang, C, Hong, W, Morgan, H, Wang, M, Sadayappan, S, Jegga, AG, Oppermann, U, Wang, Y, Huang, W, Jiang, L, Pauklin, S
Format: Journal article
Language:English
Published: Elsevier 2023

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