Lactate levels in severe malarial anaemia are associated with haemozoin-containing neutrophils and low levels of IL-12.

BACKGROUND: Hyperlactataemia is often associated with a poor outcome in severe malaria in African children. To unravel the complex pathophysiology of this condition the relationship between plasma lactate levels, parasite density, pro- and anti-inflammatory cytokines, and haemozoin-containing leuco...

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Bibliographic Details
Main Authors: Casals-Pascual, C, Kai, O, Lowe, B, English, M, Williams, T, Maitland, K, Newton, C, Peshu, N, Roberts, D
Format: Journal article
Language:English
Published: 2006