The long non-coding RNA Paupar regulates the expression of both local and distal genes.
Although some long noncoding RNAs (lncRNAs) have been shown to regulate gene expression in cis, it remains unclear whether lncRNAs can directly regulate transcription in trans by interacting with chromatin genome-wide independently of their sites of synthesis. Here, we describe the genomically local...
Main Authors: | Vance, K, Sansom, S, Lee, S, Chalei, V, Kong, L, Cooper, SE, Oliver, P, Ponting, C |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2014
|
Similar Items
-
The long non-coding RNA Dali is an epigenetic regulator of neural differentiation
by: Chalei, V, et al.
Published: (2014) -
The long non-coding RNA Paupar promotes KAP1-dependent chromatin changes and regulates olfactory bulb neurogenesis
by: Pavlaki, I, et al.
Published: (2018) -
KAP1-Paupar lncRNA chromatin regulatory complex controls subventricular zone neurogenesis
by: Alammari, F
Published: (2019) -
Genomic and transcriptional co-localization of protein-coding and long non-coding RNA pairs in the developing brain.
by: Ponjavic, J, et al.
Published: (2009) -
Investigating molecular mechanisms of Dali, an intergenic chromatin-associated lincRNA regulating genes locally and neural differentiation genome-wide
by: Chalei, V
Published: (2014)