Rhodium(I) catalysis for intermolecular alkyne hydroacylation and desymmetrisation

<p>This thesis discloses the uses and development of rhodium(I) catalysis within intermolecular hydroacylation and asymmetric [2+2+2] cycloadditions.</p> <p><b>Chapter 1</b> provides a general overview of the key methods and tethering strategies within the field rhodiu...

詳細記述

書誌詳細
第一著者: Moseley, D
その他の著者: Willis, M
フォーマット: 学位論文
言語:English
出版事項: 2022
主題:
その他の書誌記述
要約:<p>This thesis discloses the uses and development of rhodium(I) catalysis within intermolecular hydroacylation and asymmetric [2+2+2] cycloadditions.</p> <p><b>Chapter 1</b> provides a general overview of the key methods and tethering strategies within the field rhodium(I) catalysed hydroacylation.</p> <p><b>Chapter 2</b> describes the diverse synthesis of fully saturated O- and N-heterocycles through a hydroacylation/conjugate-addition sequence.</p> <p><b>Chapter 3</b> uses azine N-oxides as novel directing groups for aldehyde C–H activation within intermolecular hydroacylation reactions.</p> <p><b>Chapter 4</b> presents a short field overview of rhodium(I) catalysed [2+2+2] cycloaddition, before applying this reaction to sulfoximine desymmetrisation.</p>