Rhodium(I) catalysis for intermolecular alkyne hydroacylation and desymmetrisation
<p>This thesis discloses the uses and development of rhodium(I) catalysis within intermolecular hydroacylation and asymmetric [2+2+2] cycloadditions.</p> <p><b>Chapter 1</b> provides a general overview of the key methods and tethering strategies within the field rhodiu...
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| Format: | Thesis |
| Language: | English |
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2022
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| _version_ | 1797108008503738368 |
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| author | Moseley, D |
| author2 | Willis, M |
| author_facet | Willis, M Moseley, D |
| author_sort | Moseley, D |
| collection | OXFORD |
| description | <p>This thesis discloses the uses and development of rhodium(I) catalysis within intermolecular hydroacylation and asymmetric [2+2+2] cycloadditions.</p>
<p><b>Chapter 1</b> provides a general overview of the key methods and tethering strategies within the field rhodium(I) catalysed hydroacylation.</p>
<p><b>Chapter 2</b> describes the diverse synthesis of fully saturated O- and N-heterocycles through a hydroacylation/conjugate-addition sequence.</p>
<p><b>Chapter 3</b> uses azine N-oxides as novel directing groups for aldehyde C–H activation within intermolecular hydroacylation reactions.</p>
<p><b>Chapter 4</b> presents a short field overview of rhodium(I) catalysed [2+2+2] cycloaddition, before applying this reaction to sulfoximine desymmetrisation.</p> |
| first_indexed | 2024-03-07T07:22:12Z |
| format | Thesis |
| id | oxford-uuid:d6deae5a-71e5-4ba0-b6e9-9c01bbff0889 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T07:22:12Z |
| publishDate | 2022 |
| record_format | dspace |
| spelling | oxford-uuid:d6deae5a-71e5-4ba0-b6e9-9c01bbff08892022-10-24T12:04:06ZRhodium(I) catalysis for intermolecular alkyne hydroacylation and desymmetrisationThesishttp://purl.org/coar/resource_type/c_db06uuid:d6deae5a-71e5-4ba0-b6e9-9c01bbff0889Chemistry, OrganicSynthesisEnglishHyrax Deposit2022Moseley, DWillis, M<p>This thesis discloses the uses and development of rhodium(I) catalysis within intermolecular hydroacylation and asymmetric [2+2+2] cycloadditions.</p> <p><b>Chapter 1</b> provides a general overview of the key methods and tethering strategies within the field rhodium(I) catalysed hydroacylation.</p> <p><b>Chapter 2</b> describes the diverse synthesis of fully saturated O- and N-heterocycles through a hydroacylation/conjugate-addition sequence.</p> <p><b>Chapter 3</b> uses azine N-oxides as novel directing groups for aldehyde C–H activation within intermolecular hydroacylation reactions.</p> <p><b>Chapter 4</b> presents a short field overview of rhodium(I) catalysed [2+2+2] cycloaddition, before applying this reaction to sulfoximine desymmetrisation.</p> |
| spellingShingle | Chemistry, Organic Synthesis Moseley, D Rhodium(I) catalysis for intermolecular alkyne hydroacylation and desymmetrisation |
| title | Rhodium(I) catalysis for intermolecular alkyne hydroacylation and desymmetrisation |
| title_full | Rhodium(I) catalysis for intermolecular alkyne hydroacylation and desymmetrisation |
| title_fullStr | Rhodium(I) catalysis for intermolecular alkyne hydroacylation and desymmetrisation |
| title_full_unstemmed | Rhodium(I) catalysis for intermolecular alkyne hydroacylation and desymmetrisation |
| title_short | Rhodium(I) catalysis for intermolecular alkyne hydroacylation and desymmetrisation |
| title_sort | rhodium i catalysis for intermolecular alkyne hydroacylation and desymmetrisation |
| topic | Chemistry, Organic Synthesis |
| work_keys_str_mv | AT moseleyd rhodiumicatalysisforintermolecularalkynehydroacylationanddesymmetrisation |