Monoclonal antibodies for the induction of transplantation tolerance.
Non-lytic antibodies to CD4 and certain other T cell adhesion receptors can guide the immune system to become tolerant to foreign antigens, and to regain tolerance in autoimmunity. Tolerance is maintained lifelong through the action of regulatory T cells that in turn can influence naive T cells to a...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1993
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| _version_ | 1797097528914608128 |
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| author | Waldmann, H Cobbold, S |
| author_facet | Waldmann, H Cobbold, S |
| author_sort | Waldmann, H |
| collection | OXFORD |
| description | Non-lytic antibodies to CD4 and certain other T cell adhesion receptors can guide the immune system to become tolerant to foreign antigens, and to regain tolerance in autoimmunity. Tolerance is maintained lifelong through the action of regulatory T cells that in turn can influence naive T cells to acquire the same regulatory properties. A fuller understanding of the molecular basis of infectious tolerance could lead to the design of better immunosuppressive protocols. |
| first_indexed | 2024-03-07T04:56:50Z |
| format | Journal article |
| id | oxford-uuid:d6e117e2-2bcb-4e93-81bd-cf1b39726284 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:56:50Z |
| publishDate | 1993 |
| record_format | dspace |
| spelling | oxford-uuid:d6e117e2-2bcb-4e93-81bd-cf1b397262842022-03-27T08:37:02ZMonoclonal antibodies for the induction of transplantation tolerance.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d6e117e2-2bcb-4e93-81bd-cf1b39726284EnglishSymplectic Elements at Oxford1993Waldmann, HCobbold, SNon-lytic antibodies to CD4 and certain other T cell adhesion receptors can guide the immune system to become tolerant to foreign antigens, and to regain tolerance in autoimmunity. Tolerance is maintained lifelong through the action of regulatory T cells that in turn can influence naive T cells to acquire the same regulatory properties. A fuller understanding of the molecular basis of infectious tolerance could lead to the design of better immunosuppressive protocols. |
| spellingShingle | Waldmann, H Cobbold, S Monoclonal antibodies for the induction of transplantation tolerance. |
| title | Monoclonal antibodies for the induction of transplantation tolerance. |
| title_full | Monoclonal antibodies for the induction of transplantation tolerance. |
| title_fullStr | Monoclonal antibodies for the induction of transplantation tolerance. |
| title_full_unstemmed | Monoclonal antibodies for the induction of transplantation tolerance. |
| title_short | Monoclonal antibodies for the induction of transplantation tolerance. |
| title_sort | monoclonal antibodies for the induction of transplantation tolerance |
| work_keys_str_mv | AT waldmannh monoclonalantibodiesfortheinductionoftransplantationtolerance AT cobbolds monoclonalantibodiesfortheinductionoftransplantationtolerance |