Pyridine nucleotide regulation of the KATP channel Kir6.2/SUR1 expressed in Xenopus oocytes.

Pyridine nucleotide regulation of the KATP channel Kir6.2/SUR1 expressed in Xenopus oocytes.

The pancreatic beta-cell type of ATP-sensitive potassium (KATP) channel (Kir6.2/SUR1) is inhibited by intracellular ATP and ADP, which bind to the Kir6.2 subunit, and is activated by Mg-nucleotide interaction with the regulatory sulphonylurea receptor subunits (SUR1). The nicotinamide adenine dinucl...

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Bibliografiske detaljer
Main Authors:	Dabrowski, M, Trapp, S, Ashcroft, F
Format:	Journal article
Sprog:	English
Udgivet:	2003

Lignende værker

Phentolamine block of KATP channels is mediated by Kir6.2.
af: Proks, P, et al.
Udgivet: (1997)

Mapping the architecture of the ATP-binding site of the KATP channel subunit Kir6.2.
af: Dabrowski, M, et al.
Udgivet: (2004)

A cytosolic factor that inhibits KATP channels expressed in Xenopus oocytes by impairing Mg-nucleotide activation by SUR1.
af: Tammaro, P, et al.
Udgivet: (2009)

Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP.
af: Proks, P, et al.
Udgivet: (1999)

The Kir6.2-F333I mutation differentially modulates KATP channels composed of SUR1 or SUR2 subunits.
af: Tammaro, P, et al.
Udgivet: (2007)

Glimepiride block of Kir6.2/SUR1 Kir6.2/SUR2A and Kir6.2/SUR2A and Kir6.2/SUR2B K-ATP channels.
af: Ashcroft, F, et al.
Udgivet: (2001)

3-D structural and functional characterization of the purified KATP channel complex Kir6.2-SUR1.
af: Mikhailov, M, et al.
Udgivet: (2005)

A mutation in the ATP-binding site of the Kir6.2 subunit of the KATP channel alters coupling with the SUR2A subunit.
af: Tammaro, P, et al.
Udgivet: (2007)

Time-dependent activation of Kir6.2/SUR2A channels but not Kir6.2/SUR1 channels in the presence of ATP
af: Ashcroft, F, et al.
Udgivet: (2001)

Photobiomodulation on KATP Channels of Kir6.2-Transfected HEK-293 Cells
af: Fu-qing Zhong, et al.
Udgivet: (2014-01-01)

Effects of mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel.
af: Reimann, F, et al.
Udgivet: (2001)

Time-dependent activation of KIR6.2/SUR2A channels but not KIR6.2/SUR1 channels in the presence of MgATP
af: Song, D, et al.
Udgivet: (2001)

Functional analysis of a structural model of the ATP-binding site of the KATP channel Kir6.2 subunit.
af: Antcliff, J, et al.
Udgivet: (2005)

Dynamic duo: Kir6 and SUR in KATP channel structure and function
af: Bruce L. Patton, et al.
Udgivet: (2024-12-01)

Reduced expression of Kir6.2/SUR2A subunits explains KATP deficiency in K+-depleted rats.
af: Tricarico, D, et al.
Udgivet: (2008)

Nucleotide modulation of pinacidil stimulation of the cloned K(ATP) channel Kir6.2/SUR2A.
af: Gribble, F, et al.
Udgivet: (2000)

A novel SUR1/Kir6.2 specific K-ATP channel opener
af: Dabrowski, M, et al.
Udgivet: (2001)

CL-705G: a novel chemical Kir6.2-specific KATP channel opener
af: Ivan Gando, et al.
Udgivet: (2023-06-01)

Structure of an open KATP channel reveals tandem PIP2 binding sites mediating the Kir6.2 and SUR1 regulatory interface
af: Camden M. Driggers, et al.
Udgivet: (2024-03-01)

Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor.
af: Tucker, S, et al.
Udgivet: (1997)

Kir6.2 mutations causing neonatal diabetes provide new insights into Kir6.2-SUR1 interactions.
af: Tammaro, P, et al.
Udgivet: (2005)

Mapping the architecture of the ATP-binding site of Kir6.2
af: Dabrowski, M, et al.
Udgivet: (2002)

Direct interaction of Na-azide with the KATP channel.
af: Trapp, S, et al.
Udgivet: (2000)

Identification of residues contributing to the ATP binding site of Kir6.2.
af: Trapp, S, et al.
Udgivet: (2003)

The N-terminus of Kir6.2 is involved in coupling to SUR1
af: Reimann, F, et al.
Udgivet: (1999)

Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetes.
af: Girard, C, et al.
Udgivet: (2009)

Nucleotide modulation of pinacidil stimulation of cloned KATP channels
af: Reimann, F, et al.
Udgivet: (2000)

The effect of signal pathways on the neural KATP subunits SUR1/Kir6.2 expression induced by Aβ1-42
af: LI Yan⁃ju, et al.
Udgivet: (2021-11-01)

Altered functional properties of KATP channel conferred by a novel splice variant of SUR1.
af: Sakura, H, et al.
Udgivet: (1999)

Mutations in the genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) in diabetes mellitus and hyperinsulinism.
af: Gloyn, A, et al.
Udgivet: (2006)

An in-frame deletion in Kir6.2 (KCNJ11) causing neonatal diabetes reveals a site of interaction between Kir6.2 and SUR1.
af: Craig, T, et al.
Udgivet: (2009)

The Kir6.2-F333I mutation differentially modulates K-ATP channels composed of SUR1 or SUR2 subunits
af: Tammaro, P, et al.
Udgivet: (2007)

The Kir6.2-F333I mutation differentially modulates K ATP channels composed of SUR1 and SUR2 subunits
af: Tammaro, P, et al.
Udgivet: (2007)

Structure-function studies of the fast gating kinetics of the cloned ATP-sensitive potassium channel, Kir6.2/SUR1
af: Proks, P, et al.
Udgivet: (2001)

A universally conserved residue in the SUR1 subunit of the KATP channel is essential for translating nucleotide binding at SUR1 into channel opening.
af: De Wet, H, et al.
Udgivet: (2012)

The role of lysine 185 in the kir6.2 subunit of the ATP-sensitive channel in channel inhibition by ATP.
af: Reimann, F, et al.
Udgivet: (1999)

Overlapping distribution of K(ATP) channel-forming Kir6.2 subunit and the sulfonylurea receptor SUR1 in rodent brain.
af: Karschin, C, et al.
Udgivet: (1997)

Focus on Kir6.2: a key component of the ATP-sensitive potassium channel.
af: Haider, S, et al.
Udgivet: (2005)

Molecular determinants of KATP channel inhibition by ATP.
af: Tucker, S, et al.
Udgivet: (1998)

Interaction of the cytosolic domains of the Kir6.2 subunit of the K(ATP) channel is modulated by sulfonylureas.
af: Lippiat, J, et al.
Udgivet: (2002)