Ammonium-directed dihydroxylation: metal-free synthesis of the diastereoisomers of 3-aminocyclohexane-1,2-diol.
The ammonium-directed, metal-free oxidation of 3-(N,N-dibenzylamino)cyclohex-1-ene with mCPBA in the presence of either trichloroacetic acid or tosic acid has been used as the key step to facilitate the synthesis of all the diastereoisomers of 3-aminocyclohexane-1,2-diol, in >98% de in each c...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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| _version_ | 1826299116310757376 |
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| author | Aciro, C Davies, S Roberts, P Russell, A Smith, A Thomson, J |
| author_facet | Aciro, C Davies, S Roberts, P Russell, A Smith, A Thomson, J |
| author_sort | Aciro, C |
| collection | OXFORD |
| description | The ammonium-directed, metal-free oxidation of 3-(N,N-dibenzylamino)cyclohex-1-ene with mCPBA in the presence of either trichloroacetic acid or tosic acid has been used as the key step to facilitate the synthesis of all the diastereoisomers of 3-aminocyclohexane-1,2-diol, in >98% de in each case. |
| first_indexed | 2024-03-07T04:57:01Z |
| format | Journal article |
| id | oxford-uuid:d6f56f3e-191e-441f-b649-a73308110543 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:57:01Z |
| publishDate | 2008 |
| record_format | dspace |
| spelling | oxford-uuid:d6f56f3e-191e-441f-b649-a733081105432022-03-27T08:37:26ZAmmonium-directed dihydroxylation: metal-free synthesis of the diastereoisomers of 3-aminocyclohexane-1,2-diol.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d6f56f3e-191e-441f-b649-a73308110543EnglishSymplectic Elements at Oxford2008Aciro, CDavies, SRoberts, PRussell, ASmith, AThomson, JThe ammonium-directed, metal-free oxidation of 3-(N,N-dibenzylamino)cyclohex-1-ene with mCPBA in the presence of either trichloroacetic acid or tosic acid has been used as the key step to facilitate the synthesis of all the diastereoisomers of 3-aminocyclohexane-1,2-diol, in >98% de in each case. |
| spellingShingle | Aciro, C Davies, S Roberts, P Russell, A Smith, A Thomson, J Ammonium-directed dihydroxylation: metal-free synthesis of the diastereoisomers of 3-aminocyclohexane-1,2-diol. |
| title | Ammonium-directed dihydroxylation: metal-free synthesis of the diastereoisomers of 3-aminocyclohexane-1,2-diol. |
| title_full | Ammonium-directed dihydroxylation: metal-free synthesis of the diastereoisomers of 3-aminocyclohexane-1,2-diol. |
| title_fullStr | Ammonium-directed dihydroxylation: metal-free synthesis of the diastereoisomers of 3-aminocyclohexane-1,2-diol. |
| title_full_unstemmed | Ammonium-directed dihydroxylation: metal-free synthesis of the diastereoisomers of 3-aminocyclohexane-1,2-diol. |
| title_short | Ammonium-directed dihydroxylation: metal-free synthesis of the diastereoisomers of 3-aminocyclohexane-1,2-diol. |
| title_sort | ammonium directed dihydroxylation metal free synthesis of the diastereoisomers of 3 aminocyclohexane 1 2 diol |
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