Prevention of food allergy - skin barrier interventions
The relationship between infant skin health and food allergy pathogenesis is the focus of intense research activity, on the basis that interventions to improve infant skin health may potentially lead to the prevention of food allergy. Current evidence does not provide conclusive findings on the mech...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
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Elsevier
2019
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_version_ | 1826299127186587648 |
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author | Kelleher, MM Tran, L Boyle, RJ |
author_facet | Kelleher, MM Tran, L Boyle, RJ |
author_sort | Kelleher, MM |
collection | OXFORD |
description | The relationship between infant skin health and food allergy pathogenesis is the focus of intense research activity, on the basis that interventions to improve infant skin health may potentially lead to the prevention of food allergy. Current evidence does not provide conclusive findings on the mechanisms of food allergy development but does support the possibility that food allergy develops through transcutaneous sensitisation to allergenic peptides. In this article, we review the evidence for this model of food allergy development, assess strategies currently being tested for prevention of food allergy through cutaneous interventions, and identify key knowledge gaps which might be explored in future work.
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first_indexed | 2024-03-07T04:57:11Z |
format | Journal article |
id | oxford-uuid:d7013fbb-26a8-4f42-b123-55ae5666fecc |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T04:57:11Z |
publishDate | 2019 |
publisher | Elsevier |
record_format | dspace |
spelling | oxford-uuid:d7013fbb-26a8-4f42-b123-55ae5666fecc2022-03-27T08:37:52ZPrevention of food allergy - skin barrier interventionsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d7013fbb-26a8-4f42-b123-55ae5666feccEnglishSymplectic ElementsElsevier2019Kelleher, MMTran, LBoyle, RJThe relationship between infant skin health and food allergy pathogenesis is the focus of intense research activity, on the basis that interventions to improve infant skin health may potentially lead to the prevention of food allergy. Current evidence does not provide conclusive findings on the mechanisms of food allergy development but does support the possibility that food allergy develops through transcutaneous sensitisation to allergenic peptides. In this article, we review the evidence for this model of food allergy development, assess strategies currently being tested for prevention of food allergy through cutaneous interventions, and identify key knowledge gaps which might be explored in future work. |
spellingShingle | Kelleher, MM Tran, L Boyle, RJ Prevention of food allergy - skin barrier interventions |
title | Prevention of food allergy - skin barrier interventions |
title_full | Prevention of food allergy - skin barrier interventions |
title_fullStr | Prevention of food allergy - skin barrier interventions |
title_full_unstemmed | Prevention of food allergy - skin barrier interventions |
title_short | Prevention of food allergy - skin barrier interventions |
title_sort | prevention of food allergy skin barrier interventions |
work_keys_str_mv | AT kellehermm preventionoffoodallergyskinbarrierinterventions AT tranl preventionoffoodallergyskinbarrierinterventions AT boylerj preventionoffoodallergyskinbarrierinterventions |