Prevention of food allergy - skin barrier interventions

The relationship between infant skin health and food allergy pathogenesis is the focus of intense research activity, on the basis that interventions to improve infant skin health may potentially lead to the prevention of food allergy. Current evidence does not provide conclusive findings on the mech...

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Main Authors: Kelleher, MM, Tran, L, Boyle, RJ
Format: Journal article
Language:English
Published: Elsevier 2019
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author Kelleher, MM
Tran, L
Boyle, RJ
author_facet Kelleher, MM
Tran, L
Boyle, RJ
author_sort Kelleher, MM
collection OXFORD
description The relationship between infant skin health and food allergy pathogenesis is the focus of intense research activity, on the basis that interventions to improve infant skin health may potentially lead to the prevention of food allergy. Current evidence does not provide conclusive findings on the mechanisms of food allergy development but does support the possibility that food allergy develops through transcutaneous sensitisation to allergenic peptides. In this article, we review the evidence for this model of food allergy development, assess strategies currently being tested for prevention of food allergy through cutaneous interventions, and identify key knowledge gaps which might be explored in future work.
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spelling oxford-uuid:d7013fbb-26a8-4f42-b123-55ae5666fecc2022-03-27T08:37:52ZPrevention of food allergy - skin barrier interventionsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d7013fbb-26a8-4f42-b123-55ae5666feccEnglishSymplectic ElementsElsevier2019Kelleher, MMTran, LBoyle, RJThe relationship between infant skin health and food allergy pathogenesis is the focus of intense research activity, on the basis that interventions to improve infant skin health may potentially lead to the prevention of food allergy. Current evidence does not provide conclusive findings on the mechanisms of food allergy development but does support the possibility that food allergy develops through transcutaneous sensitisation to allergenic peptides. In this article, we review the evidence for this model of food allergy development, assess strategies currently being tested for prevention of food allergy through cutaneous interventions, and identify key knowledge gaps which might be explored in future work.
spellingShingle Kelleher, MM
Tran, L
Boyle, RJ
Prevention of food allergy - skin barrier interventions
title Prevention of food allergy - skin barrier interventions
title_full Prevention of food allergy - skin barrier interventions
title_fullStr Prevention of food allergy - skin barrier interventions
title_full_unstemmed Prevention of food allergy - skin barrier interventions
title_short Prevention of food allergy - skin barrier interventions
title_sort prevention of food allergy skin barrier interventions
work_keys_str_mv AT kellehermm preventionoffoodallergyskinbarrierinterventions
AT tranl preventionoffoodallergyskinbarrierinterventions
AT boylerj preventionoffoodallergyskinbarrierinterventions