GluN1 hypomorph mice exhibit wide-ranging behavioral alterations

GluN1 hypomorph mice exhibit wide-ranging behavioral alterations

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The psychotomimetic effects of N-methyl-d-aspartate receptor (NMDA) antagonists such as ketamine and phencyclidine suggest a role for reduced NMDA receptor-mediated neurotransmission in schizophrenia. GluN1 'hypomorph' (GluN1 hypo) mice exhibit reduced NMDA receptor expression and have bee...

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Bibliographic Details
Main Authors:	Barkus, C, Dawson, L, Sharp, T, Bannerman, D
Format:	Journal article
Language:	English
Published:	2012

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