Identification of contact residues in the IgE binding site of human FcepsilonRIalpha.
The high-affinity receptor for immunoglobulin E (IgE), FcepsilonRI, is an alphabetagamma2 tetramer found on mast cells, basophils, and several other types of immune effector cells. The interaction of IgE with the alpha-subunit of FcepsilonRI is central to the pathogenesis of allergy. Detailed knowle...
Main Authors: | Cook, J, Henry, A, McDonnell, J, Owens, R, Sutton, B, Gould, H |
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Format: | Journal article |
Language: | English |
Published: |
1997
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