Identification of contact residues in the IgE binding site of human FcepsilonRIalpha.

The high-affinity receptor for immunoglobulin E (IgE), FcepsilonRI, is an alphabetagamma2 tetramer found on mast cells, basophils, and several other types of immune effector cells. The interaction of IgE with the alpha-subunit of FcepsilonRI is central to the pathogenesis of allergy. Detailed knowle...

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Príomhchruthaitheoirí: Cook, J, Henry, A, McDonnell, J, Owens, R, Sutton, B, Gould, H
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 1997

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