Differential response of the liver to bile acid treatment in a mouse model of Niemann-Pick disease type C

Differential response of the liver to bile acid treatment in a mouse model of Niemann-Pick disease type C

Niemann-Pick disease type C (NPC) disease is a neurodegenerative lysosomal storage disease caused by mutations in the NPC1 or NPC2 genes. Liver disease is also a common feature of NPC that can present as cholestatic jaundice in the neonatal period. Liver enzymes can remain elevated above the normal...

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Bibliografiske detaljer
Main Authors:	Nicoli, E, Smith, D, Morris, L, Platt, F
Format:	Journal article
Sprog:	English
Udgivet:	F1000Research 2017

Lignende værker

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