Charts of fetal size: limb bones.

OBJECTIVE: To construct new size charts for all fetal limb bones. DESIGN: A prospective, cross sectional study. SETTING: Ultrasound department of a large hospital. SAMPLE: 663 fetuses scanned once only for the purpose of the study at gestations between 12 and 42 weeks. METHODS: Centiles were estima...

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Main Authors: Chitty, L, Altman, D
Format: Journal article
Language:English
Published: 2002
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author Chitty, L
Altman, D
author_facet Chitty, L
Altman, D
author_sort Chitty, L
collection OXFORD
description OBJECTIVE: To construct new size charts for all fetal limb bones. DESIGN: A prospective, cross sectional study. SETTING: Ultrasound department of a large hospital. SAMPLE: 663 fetuses scanned once only for the purpose of the study at gestations between 12 and 42 weeks. METHODS: Centiles were estimated by combining separate regression models fitted to the mean and standard deviation, assuming that the measurements have a normal distribution at each gestational age. MAIN OUTCOME MEASURES: Determination of fetal limb lengths from 12 to 42 weeks of gestation. RESULTS: Size charts for fetal bones (radius, ulna, humerus, tibia, fibula, femur and foot) are presented and compared with previously published data. CONCLUSIONS: We present new size charts for fetal limb bones which take into consideration the increasing variability with gestational age. We have compared these charts with other published data; the differences seen may be largely due to methodological differences. As standards for fetal head and abdominal measurements have been published from the same population, we suggest that the use of the new charts may facilitate prenatal diagnosis of skeletal dysplasias.
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spelling oxford-uuid:d730bdf9-406f-43e5-8957-48596fcf43462022-03-27T08:39:23ZCharts of fetal size: limb bones.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d730bdf9-406f-43e5-8957-48596fcf4346EnglishSymplectic Elements at Oxford2002Chitty, LAltman, D OBJECTIVE: To construct new size charts for all fetal limb bones. DESIGN: A prospective, cross sectional study. SETTING: Ultrasound department of a large hospital. SAMPLE: 663 fetuses scanned once only for the purpose of the study at gestations between 12 and 42 weeks. METHODS: Centiles were estimated by combining separate regression models fitted to the mean and standard deviation, assuming that the measurements have a normal distribution at each gestational age. MAIN OUTCOME MEASURES: Determination of fetal limb lengths from 12 to 42 weeks of gestation. RESULTS: Size charts for fetal bones (radius, ulna, humerus, tibia, fibula, femur and foot) are presented and compared with previously published data. CONCLUSIONS: We present new size charts for fetal limb bones which take into consideration the increasing variability with gestational age. We have compared these charts with other published data; the differences seen may be largely due to methodological differences. As standards for fetal head and abdominal measurements have been published from the same population, we suggest that the use of the new charts may facilitate prenatal diagnosis of skeletal dysplasias.
spellingShingle Chitty, L
Altman, D
Charts of fetal size: limb bones.
title Charts of fetal size: limb bones.
title_full Charts of fetal size: limb bones.
title_fullStr Charts of fetal size: limb bones.
title_full_unstemmed Charts of fetal size: limb bones.
title_short Charts of fetal size: limb bones.
title_sort charts of fetal size limb bones
work_keys_str_mv AT chittyl chartsoffetalsizelimbbones
AT altmand chartsoffetalsizelimbbones