Microdissection molecular copy-number counting (microMCC)--unlocking cancer archives with digital PCR.
Most cancer genomes are characterized by the gain or loss of copies of some sequences through deletion, amplification or unbalanced translocations. Delineating and quantifying these changes is important in understanding the initiation and progression of cancer, in identifying novel therapeutic targe...
Main Authors: | McCaughan, F, Darai-Ramqvist, E, Bankier, A, Konfortov, B, Foster, N, George, P, Rabbitts, T, Kost-Alimova, M, Rabbitts, P, Dear, P |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2008
|
Similar Items
-
Interrogation of genomes by molecular copy-number counting (MCC).
by: Daser, A, et al.
Published: (2006) -
Progressive 3q amplification consistently targets SOX2 in preinvasive squamous lung cancer.
by: McCaughan, F, et al.
Published: (2010) -
Erratum: Interrogation of genomes by molecular copy-number counting (MCC) (Nature Methods (2006) vol. 3 (447-453))
by: Daser, A, et al.
Published: (2006) -
Nonreciprocal chromosomal translocations in renal cancer involve multiple DSBs and NHEJ associated with breakpoint inversion but not necessarily with transcription.
by: Ali, H, et al.
Published: (2013) -
Nonreciprocal chromosomal translocations in renal cancer involve multiple DSBs and NHEJ associated with breakpoint inversion but not necessarily with transcription
by: Ali, H, et al.
Published: (2013)