CD4+ regulatory T cells generated in vitro with IFN-{gamma} and allogeneic APC inhibit transplant arteriosclerosis.

We have developed a method to generate alloreactive regulatory T cells in vitro in the presence of interferon (IFN)-gamma and donor antigen presenting cells (APCs). We hypothesized that these IFN-gamma-conditioned T cells (Tcon) would reduce transplantation-associated arteriosclerosis. Tcon were gen...

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Autori principali: Warnecke, G, Feng, G, Goto, R, Nadig, SN, Francis, R, Wood, K, Bushell, A
Natura: Journal article
Lingua:English
Pubblicazione: 2010