The endoplasmic reticulum plays a key role in α-cell intracellular Ca2+ dynamics and glucose-regulated glucagon secretion in mouse islets

The endoplasmic reticulum plays a key role in α-cell intracellular Ca2+ dynamics and glucose-regulated glucagon secretion in mouse islets

<p>Glucagon is secreted by pancreatic α-cells to counteract hypoglycaemia. How glucose regulates glucagon secretion remains unclear. Here, using mouse islets, we studied the role of transmembrane and endoplasmic reticulum (ER) Ca<sup>2+</sup> on intrinsic &al...

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Dettagli Bibliografici
Autori principali:	Acreman, S, Ma, J, Denwood, G, Gao, R, Tarasov, A, Rorsman, P, Zhang, Q
Natura:	Journal article
Lingua:	English
Pubblicazione:	Cell Press 2024

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