The endoplasmic reticulum plays a key role in α-cell intracellular Ca2+ dynamics and glucose-regulated glucagon secretion in mouse islets
<p>Glucagon is secreted by pancreatic α-cells to counteract hypoglycaemia. How glucose regulates glucagon secretion remains unclear. Here, using mouse islets, we studied the role of transmembrane and endoplasmic reticulum (ER) Ca<sup>2+</sup> on intrinsic &al...
Main Authors: | Acreman, S, Ma, J, Denwood, G, Gao, R, Tarasov, A, Rorsman, P, Zhang, Q |
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Format: | Journal article |
Language: | English |
Published: |
Cell Press
2024
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