Different pathways of human T-cell activation revealed by PHA-P and PHA-M.
Antigen-specific T-cell activation is mediated via the CD3-Ti (antigen receptor) complex, and monoclonal antibodies to both CD3 and Ti cause a rapid rise in intracellular Ca2+. This calcium mobilization is not inhibited by monoclonal antibodies to CD2. The rise in calcium mobilization induced by pur...
Main Authors: | O'Flynn, K, Russul-Saib, M, Ando, I, Wallace, D, Beverley, P, Boylston, A, Linch, D |
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格式: | Journal article |
語言: | English |
出版: |
1986
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