Acute hypoxia and osteoclast activity: a balance between enhanced resorption and increased apoptosis.

Osteoclasts are the primary mediators of pathological bone resorption in many conditions in which micro-environmental hypoxia is associated with disease progression. However, effects of hypoxia on human osteoclast activity have not been reported. Mature human osteoclasts were differentiated from per...

Descrición completa

Detalles Bibliográficos
Main Authors: Knowles, H, Athanasou, N
Formato: Journal article
Idioma:English
Publicado: 2009