Sequence-specific assembly of FtsK hexamers establishes directional translocation on DNA.
FtsK is a homohexameric, RecA-like dsDNA translocase that plays a key role in bacterial chromosome segregation. The FtsK regulatory γ-subdomain determines directionality of translocation through its interaction with specific 8 base pair chromosomal sequences [(KOPS); FtsK Orienting/Polarizing Sequen...
Main Authors: | Graham, J, Sherratt, D, Szczelkun, MD |
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Format: | Journal article |
Language: | English |
Published: |
2010
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