Investigating the role of the fat mass and obesity associated gene (Fto) in obesity

<p>In 2007, a genome wide association study identified a SNP in intron 1 of FTO with increased BMI. Homozygous risk allele carriers are on average three kg heavier than those homozygous for the protective allele. Mouse models have been made, including a conditional knockout, which is lean when...

وصف كامل

التفاصيل البيبلوغرافية
المؤلف الرئيسي: McMurray, F
مؤلفون آخرون: Cox, R
التنسيق: أطروحة
اللغة:English
منشور في: 2013
الموضوعات: