Investigating the role of the fat mass and obesity associated gene (Fto) in obesity
<p>In 2007, a genome wide association study identified a SNP in intron 1 of FTO with increased BMI. Homozygous risk allele carriers are on average three kg heavier than those homozygous for the protective allele. Mouse models have been made, including a conditional knockout, which is lean when...
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| Format: | Thesis |
| Language: | English |
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2013
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